Monitoring the Efficacy of Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium Falciparum Malaria by Kelch 13 Gene Mutations in Bangui, Central African Republic

• Published in: Médecine tropicale et santé internationale Vol. 1; no. 1
• Main Authors: Nambei, W S, Biago, U, Balizou, O, Pounguinza, S, Moyen, M, Ndoua, C, Gody, J C
• Format: Journal Article
• Language: French
• Published: France 31.03.2021
• Subjects: Antimalarials - therapeutic use; Artemether - therapeutic use; Artemether, Lumefantrine Drug Combination - therapeutic use; Artemisinins - therapeutic use; Central African Republic; Child; Cross-Sectional Studies; Drug Combinations; Ethanolamines - therapeutic use; Fluorenes - therapeutic use; Humans; Malaria - drug therapy; Malaria, Falciparum - drug therapy; Mutation; Treatment Outcome; Central African Republic; Plasmodium falciparum; Bangui; Uncomplicated malaria; Central African Republic; Children; Hospital; K13; Sub-Saharan Africa; Artemether-lumefantrine

Drug resistance remains a major challenge for the management of malaria. This study investigated the efficacy of antimalarial combination artemether-lumefantrine (AL) in the treatment of uncomplicated malaria in Bangui, Central African Republic. An evaluative cross-sectional study was conducted betw...