The message of the survival curves: I. Composite analysis of long-term treatment studies in bipolar disorder

• Published in: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakológiai Egyesület lapja Vol. 14; no. 3; p. 155
• Main Authors: Frecska, Ede, Kovacs, Attila Istvan, Balla, Petra, Falussy, Linda, Ferencz, Akos, Varga, Zsofia
• Format: Journal Article
• Language: English
• Published: Hungary 01.09.2012
• Subjects: Affect; Antipsychotic Agents - therapeutic use; Bipolar Disorder - drug therapy; Bipolar Disorder - mortality; Bipolar Disorder - psychology; Controlled Clinical Trials as Topic; Disease-Free Survival; Drug Therapy, Combination; Humans; Kaplan-Meier Estimate; Life Tables; Long-Term Care - methods; Recurrence; Time Factors

There is a shortage of studies analyzing the time course of recurrent episodes and comparing effectiveness of long-term treatments in bipolar disorder. 'Number needed to treat' (NNT) analyses have been proven to be useful for clinically meaningful comparisons, but results vary considerably...