Antiviral properties of basidiomycetes metabolites

• Published in: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] Vol. 59; no. 7-8; pp. 41 - 48
• Main Authors: Avtonomova, A V, Krasnopolskaya, L M
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2014
• Subjects: Agaricus - chemistry; Agaricus - metabolism; Antiviral Agents - isolation & purification; Antiviral Agents - metabolism; Antiviral Agents - pharmacology; Grifola - chemistry; Grifola - metabolism; Hepatitis B virus - drug effects; Hepatitis B virus - physiology; Herpesvirus 1, Human - drug effects; Herpesvirus 1, Human - physiology; Herpesvirus 2, Human - drug effects; Herpesvirus 2, Human - physiology; Herpesvirus 4, Human - drug effects; Herpesvirus 4, Human - physiology; HIV - drug effects; HIV - physiology; Humans; Immunologic Factors - isolation & purification; Immunologic Factors - metabolism; Immunologic Factors - pharmacology; Metabolome - physiology; Orthomyxoviridae - drug effects; Orthomyxoviridae - physiology; Reishi - chemistry; Reishi - metabolism; Shiitake Mushrooms - chemistry; Shiitake Mushrooms - metabolism; Vesiculovirus - drug effects; Vesiculovirus - physiology
• ISSN: 0235-2990

The data on the antiviral action of the Ganoderma lucidum, Lentinus edodes, Grifola frondosa, Agaricus brasiliensis and other basidiomycetes metabolites are summurized. The metabolites of these species of basidiomycetes exhibit a direct antiviral effect on herpes simplex virus types I and II, human immunodeficiency virus (HIV), hepatitis B virus, vesicular stomatitis virus, influenza virus, Epstein-Barr virus, and others. Moreover, metabolites of basidiomycetes increased antiviral immunity.