Common variant in FUT2 gene is associated with levels of vitamin B(12) in Indian population

• Published in: Gene Vol. 515; no. 1; pp. 224 - 228
• Main Authors: Tanwar, Vinay Singh, Chand, Mandeep P, Kumar, Jitender, Garg, Gaurav, Seth, Sandeep, Karthikeyan, Ganesan, Sengupta, Shantanu
• Format: Journal Article
• Language: English
• Published: Netherlands 15.02.2013
• Subjects: Adult; Alleles; European Continental Ancestry Group - genetics; Genetic Association Studies; Genotype; Humans; India; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Polymorphism, Single Nucleotide; Polynucleotide Adenylyltransferase - genetics; Vitamin B 12 - blood; Vitamin B 12 - metabolism; India

Vitamin B(12) is an essential micronutrient synthesized by microorganisms. Mammals including humans have evolved ways for transport and absorption of this vitamin. Deficiency of vitamin B(12) (either due to low intake or polymorphism in genes involved in absorption and intracellular transport of thi...