Effect of Linggui Zhugan Decoction-containing serum on mitochondrial oxidative stress in cardiomyocytes: an exploration based on Nrf2/BNIP3 signaling pathway

• Published in: Zhongguo zhongyao zazhi Vol. 47; no. 12; p. 3303
• Main Authors: Tang, Tong-Juan, Wang, Xiang, Zhou, Peng, Wang, Liang, Shi, Hui, Huang, Jin-Ling
• Format: Journal Article
• Language: Chinese
• Published: China 01.06.2022
• Subjects: Apoptosis; Mitochondrial Permeability Transition Pore; Myocytes, Cardiac; NF-E2-Related Factor 2 - genetics; NF-E2-Related Factor 2 - metabolism; Oxidative Stress; Reactive Oxygen Species - metabolism; Signal Transduction; Linggui Zhugan Decoction(LGZGD); apoptosis; reactive oxygen species(ROS); mitochondria; oxidative stress

This study aimed to explore the effect of Linggui Zhugan Decoction(LGZGD)-containing serum on mitochondrial oxidative stress in cardiomyocytes based on the NF-E2-related factor2(Nrf2)/Bcl-2/adenovirus E1 B 19 kDa interacting protein(BNIP3) signaling pathway. After the preparation of LGZGD-containing...