Transcriptional control of ciliogenesis in animal development

• Published in: Biologie aujourd'hui Vol. 206; no. 3; p. 205
• Main Authors: Jerber, Julie, Thomas, Joëlle, Durand, Bénédicte
• Format: Journal Article
• Language: French
• Published: France 2012
• Subjects: Animals; Cilia - genetics; Cilia - physiology; DNA-Binding Proteins - genetics; DNA-Binding Proteins - physiology; Forkhead Transcription Factors - genetics; Forkhead Transcription Factors - physiology; Gene Expression Regulation, Developmental; Humans; Morphogenesis; Regulatory Factor X Transcription Factors; Transcription Factors - genetics; Transcription Factors - physiology; Transcription, Genetic - genetics

Cilia and flagella are eukaryotic organelles with a conserved structure and function from unicellular organisms to human. In animals, different types of cilia can be found and cilia assembly during development is a highly dynamic process. Ciliary defects in human lead to a wide spectrum of diseases...