Evaluation of Mean Shift, ComBat, and CycleGAN for Harmonizing Brain Connectivity Matrices Across Sites

• Published in: ArXiv.org
• Main Authors: Xu, Hanliang, Newlin, Nancy R, Kim, Michael E, Gao, Chenyu, Kanakaraj, Praitayini, Krishnan, Aravind R, Remedios, Lucas W, Khairi, Nazirah Mohd, Pechman, Kimberly, Archer, Derek, Hohman, Timothy J, Jefferson, Angela L, Isgum, Ivana, Huo, Yuankai, Moyer, Daniel, Schilling, Kurt G, Landman, Bennett A
• Format: Journal Article
• Language: English
• Published: United States 24.01.2024
• Subjects: graph measure; mean shift; ComBat; connectome; Connectivity matrix; dMRI; harmonization; CycleGAN

Connectivity matrices derived from diffusion MRI (dMRI) provide an interpretable and generalizable way of understanding the human brain connectome. However, dMRI suffers from inter-site and between-scanner variation, which impedes analysis across datasets to improve robustness and reproducibility of...