The exclusion of older patients from clinical trials regarding heart failure. Causes and consequences

• Published in: Recenti progressi in medicina Vol. 103; no. 3; p. 103
• Main Authors: Cherubini, Antonio, Cerenzia, Annarita, Zengarini, Elisa
• Format: Journal Article
• Language: Italian
• Published: Italy 01.03.2012
• Subjects: Aged; Clinical Trials as Topic - ethics; Clinical Trials as Topic - standards; Heart Failure; Humans; Patient Selection - ethics

Older subjects are commonly excluded from clinical trials, that are the gold standard to assess the efficacy and safety of new drugs and non pharmacological therapies. The consequence is the lack of evidence about the optimal drug therapy in this population, who makes the highest consumption of drug...