CDK9 has the intrinsic property to shuttle between nucleus and cytoplasm, and enhanced expression of cyclin T1 promotes its nuclear localization
CDK9 in association with cyclin T constitutes the P-TEFb complex that stimulates transcription elongation of RNAPII transcripts by phosphorylation of the CTD of RNAPII. Here we report subcellular distribution of P-TEFb in terms of localization of CDK9 and cyclin T1. We found that cyclin T1 is exclus...
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Published in | Journal of cellular physiology Vol. 192; no. 2; pp. 209 - 215 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
01.08.2002
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Subjects | |
Online Access | Get full text |
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