Neurological defects and developmental disorders following neonatal extracorporeal membrane oxygenation: results of a follow-up study after 5 years

• Published in: Nederlands tijdschrift voor geneeskunde Vol. 152; no. 4; p. 207
• Main Authors: Hanekamp, M N, Mazer, P, van der Cammen-van Zijp, M H M, van Kessel-Feddema, B J M, Nijhuis-van der Sanden, M W G, Knuijt, S, Zegers-Verstraeten, J L A, Gischler, S J, Tibboel, D, Kollée, L A A
• Format: Journal Article
• Language: Dutch
• Published: Netherlands 26.01.2008
• Subjects: Child, Preschool; Developmental Disabilities - epidemiology; Extracorporeal Membrane Oxygenation - adverse effects; Female; Follow-Up Studies; Humans; Infant, Newborn; Male; Nervous System Diseases - epidemiology; Netherlands - epidemiology; Prevalence; Severity of Illness Index; Netherlands
• ISSN: 0028-2162

Descriptive study of the development of children 5 years after neonatal extracorporeal membrane oxygenation (ECMO). Descriptive. 98 treated children were subjected to a paediatric, neurological, psychological, physiotherapeutic and logopaedic examination. The children came from 2 Dutch ECMO-centres (the Erasmus MC-Sophia Children's Hospital in Rotterdam and the University Medical Centre St Radboud in Nijmegen, The Netherlands). Neurological disorders were found in 17 of the 98 investigated children, and in 6 cases these were serious. Among the remaining 92 children, 24 had motor disorders and 11 had delayed cognitive development. The average IQ (100.5) was within the normal range. A significant proportion ofthe children that had been treated with ECMO had long-term morbidity in the form of neurological defects and developmental disorders.