Genotoxicity effect of chronic lead exposure assessed using the comet assay

• Published in: Medycyna pracy Vol. 56; no. 4; p. 295
• Main Authors: Steinmetz-Beck, Aleksandra, Szahidewicz-Krupska, Ewa, Beck, Bogusław, Poreba, Rafał, Andrzejak, Ryszard
• Format: Journal Article
• Language: Polish
• Published: Poland 2005
• Subjects: Adult; Aged; Analysis of Variance; Comet Assay; Comorbidity; DNA Damage; Environmental Monitoring - methods; Epidemiological Monitoring; Humans; Lead Poisoning - blood; Lead Poisoning - diagnosis; Lead Poisoning - epidemiology; Lead Poisoning - genetics; Male; Middle Aged; Occupational Diseases - blood; Occupational Diseases - diagnosis; Occupational Diseases - epidemiology; Occupational Diseases - genetics; Occupational Exposure - analysis; Severity of Illness Index; Smoking - epidemiology

Lead, an important xenobiotic, is globally well distributed. The IARC has classified inorganic lead compounds as possibly carcinogenic to humans. The study was designed to assess genotoxic effects in workers occupationally exposed to Pb. The study comprised 62 male workers with chronic exposure to l...