Reconstruction of defects at the neuromuscular junction

Loss of muscle tissue at the area of the neuromuscular junction after tumor resection or after trauma precludes the reconstruction with conventional nerve grafts, because the distal nerve stump is absent. For these cases, we recommend direct insertion of the nerve grafts into the muscle. We describe...

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Bibliographic Details
Published inHandchirurgie, Mikrochirurgie, plastische Chirurgie Vol. 35; no. 2; p. 127
Main Authors Lassner, F, Becker, M, Fansa, H, Mawrin, C, Pallua, N
Format Journal Article
LanguageGerman
Published Germany 01.03.2003
Subjects
Adult
Follow-Up Studies
Humans
Muscle Neoplasms - surgery
Muscle, Skeletal - innervation
Nerve Regeneration - physiology
Nerve Transfer - methods
Neuromuscular Junction - injuries
Neuromuscular Junction - physiopathology
Neuromuscular Junction - surgery
Neuromuscular Junction Diseases - etiology
Neuromuscular Junction Diseases - surgery
Peripheral Nerves - transplantation
Postoperative Complications - etiology
Postoperative Complications - surgery
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Summary:Loss of muscle tissue at the area of the neuromuscular junction after tumor resection or after trauma precludes the reconstruction with conventional nerve grafts, because the distal nerve stump is absent. For these cases, we recommend direct insertion of the nerve grafts into the muscle. We describe a standardized technique, which has been performed in 19 patients and led to a mean motor recovery of grade M4 after Highet. The key procedure of this technique is the interfascicular dissection of the nerve grafts, which allows a wide distribution of the grafts into the muscle tissue.
ISSN:0722-1819
1439-3980