Histocompatibility HLA system of man. Consideration in the light of current concepts. I. Organization and polymorphism

• Published in: Przeglad lekarski Vol. 58; no. 5; p. 459
• Main Authors: Kedzierska, A, Turowski, G
• Format: Journal Article
• Language: Polish
• Published: Poland 2001
• Subjects: Gene Expression; Gene Frequency; Genetic Markers; HLA Antigens - genetics; Humans; Point Mutation - genetics; Polymorphism, Genetic - genetics

The HLA system, which represents the major histocompatibility complex (MHC) of man, encompasses approximately one thousandth of the human genome and is localised on the short arm of chromosome 6 (band 6p 21.3). The HLA gene complex shows an extreme polymorphism which can be demonstrated by molecular...