Results of a prospective randomized investigation [Russia (St.Petersburg)/WHOto evaluate the significance of self-examination for the early detection of breast cancer

Indications for puncture or excision biopsy were significantly higher in the study group (7.5%) as compared with control (3.5%) (p < 0.01) in a randomized prospective controlled trial of a comprehensive breast cancer screening (123,748) carried out in the framework of a self-examination education...

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Published inVoprosy onkologij Vol. 49; no. 4; p. 434
Main Authors Semiglazov, V F, Manikhas, A G, Moiseenko, V M, Protsenko, S A, Kharikova, R S, Seleznev, I K, Popova, R T, Migmanova, N Sh, Orlov, A A, Barash, N Iu, Ivanova, O A, Ivanov, V G
Format Journal Article
LanguageRussian
Published Russia (Federation) 2003
Subjects
Adult
Breast Neoplasms - diagnosis
Breast Neoplasms - mortality
Breast Self-Examination
Female
Health Education
Humans
Middle Aged
Mortality - trends
Program Evaluation
Prospective Studies
Russia - epidemiology
Survival Rate
World Health Organization
Russia
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Summary:Indications for puncture or excision biopsy were significantly higher in the study group (7.5%) as compared with control (3.5%) (p < 0.01) in a randomized prospective controlled trial of a comprehensive breast cancer screening (123,748) carried out in the framework of a self-examination education program. In the self-examination group, detection rates were higher both for benign (1.1%) and malignant (0.85%) tumors than in control (0.5% and 0.69%, respectively) (p < 0.05). Early stage (T1NOMO, Tis) distribution difference in the study group and controls was insignificant--23 and 17.6%, respectively. Compliance with the program requirements including monthly or bimonthly self-examination was followed by higher 15-year survival rates (53.2%) in 70-75% as compared with controls(45.8%) (p = 0.05105): yet it did not affect mortality.
ISSN:0507-3758