Defect repair in rat mandible with hydroxyapatite cement compared to small intestine submucosa
The aim of this study was to evaluate the bone formation in surgically created defects of rabbit mandibles by synthetic hydroxyapatite of calcium compared to small Intestine Submucosa. 24 mice lineage Wisthar-Furth were used. A bony defect of 0,75 cm x 1,5 cm in mandibular ramus was accomplished in...
Saved in:
Published in | Brazilian journal of otorhinolaryngology Vol. 72; no. 2; pp. 195 - 199 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Brazil
01.03.2006
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The aim of this study was to evaluate the bone formation in surgically created defects of rabbit mandibles by synthetic hydroxyapatite of calcium compared to small Intestine Submucosa.
24 mice lineage Wisthar-Furth were used. A bony defect of 0,75 cm x 1,5 cm in mandibular ramus was accomplished in all animals. The hydroxyapatite implants were placed on the left hemimandiblein group I, small Intestine submucosa in group II, and the right served as control. The euthanasia was accomplished in the 40 degrees postoperative day, it was proceeded the macroscopic and histological analysis.
medium length in millimeters of the hemimandibless in the hydroxyapatite group was of 3,75, in the small intestine submucosa 3,03 and the control group was of 2,63 (p: 0,022). Histomorphometry study revealed new bone grown in 76,64% of the total area in hydroxyapatite group (p: 0,022). In Small Intestinal submucosa group new bone grown in 63,64% do total (p: 0,0022).
satisfactory bone integration was observed of the synthetic hydroxyapatite in that experimental model. Small intestinal submucosa cause osteoinduction
using hydroxyapatite of calcium resulted in formation of significantly larger volume fractions of new bone when compared to small intestinal submucosa group. |
---|---|
AbstractList | AIMThe aim of this study was to evaluate the bone formation in surgically created defects of rabbit mandibles by synthetic hydroxyapatite of calcium compared to small Intestine Submucosa. MATERIAL AND METHOD24 mice lineage Wisthar-Furth were used. A bony defect of 0,75 cm x 1,5 cm in mandibular ramus was accomplished in all animals. The hydroxyapatite implants were placed on the left hemimandiblein group I, small Intestine submucosa in group II, and the right served as control. The euthanasia was accomplished in the 40 degrees postoperative day, it was proceeded the macroscopic and histological analysis. RESULTSmedium length in millimeters of the hemimandibless in the hydroxyapatite group was of 3,75, in the small intestine submucosa 3,03 and the control group was of 2,63 (p: 0,022). Histomorphometry study revealed new bone grown in 76,64% of the total area in hydroxyapatite group (p: 0,022). In Small Intestinal submucosa group new bone grown in 63,64% do total (p: 0,0022). DISCUSSIONsatisfactory bone integration was observed of the synthetic hydroxyapatite in that experimental model. Small intestinal submucosa cause osteoinduction CONCLUSIONusing hydroxyapatite of calcium resulted in formation of significantly larger volume fractions of new bone when compared to small intestinal submucosa group. The aim of this study was to evaluate the bone formation in surgically created defects of rabbit mandibles by synthetic hydroxyapatite of calcium compared to small Intestine Submucosa. 24 mice lineage Wisthar-Furth were used. A bony defect of 0,75 cm x 1,5 cm in mandibular ramus was accomplished in all animals. The hydroxyapatite implants were placed on the left hemimandiblein group I, small Intestine submucosa in group II, and the right served as control. The euthanasia was accomplished in the 40 degrees postoperative day, it was proceeded the macroscopic and histological analysis. medium length in millimeters of the hemimandibless in the hydroxyapatite group was of 3,75, in the small intestine submucosa 3,03 and the control group was of 2,63 (p: 0,022). Histomorphometry study revealed new bone grown in 76,64% of the total area in hydroxyapatite group (p: 0,022). In Small Intestinal submucosa group new bone grown in 63,64% do total (p: 0,0022). satisfactory bone integration was observed of the synthetic hydroxyapatite in that experimental model. Small intestinal submucosa cause osteoinduction using hydroxyapatite of calcium resulted in formation of significantly larger volume fractions of new bone when compared to small intestinal submucosa group. |
Author | Sass, Sheila Noronha, Lúcia Soccol, Andréa Thomaz Bettega, Silvio Scholz, Marcos Renato Mocellin, Marcos Soccol, Vanete T |
Author_xml | – sequence: 1 givenname: Andréa Thomaz surname: Soccol fullname: Soccol, Andréa Thomaz organization: University Hospital of Paraná, Brazil – sequence: 2 givenname: Silvio surname: Bettega fullname: Bettega, Silvio – sequence: 3 givenname: Lúcia surname: Noronha fullname: Noronha, Lúcia – sequence: 4 givenname: Sheila surname: Sass fullname: Sass, Sheila – sequence: 5 givenname: Vanete T surname: Soccol fullname: Soccol, Vanete T – sequence: 6 givenname: Marcos Renato surname: Scholz fullname: Scholz, Marcos Renato – sequence: 7 givenname: Marcos surname: Mocellin fullname: Mocellin, Marcos |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/16951852$$D View this record in MEDLINE/PubMed |
BookMark | eNo1kM1KxDAYRbMYcX70FSQrd4U0bb4mSxl_YcDNrC1p8pWJtElNUnTe3oLj6m7OvRzulqx88Lgim1IyWUhQ9ZpsU_pkDBrWiGuyLkGJUgq-IR-P2KPJNOKkXaTO06gzHbW3rhuQfrt8oqezjeHnrCedXUZqcESfqQnjpCNamgNNox6GpZwxZeeRprkbZxOSviFXvR4S3l5yR47PT8f9a3F4f3nbPxyKSdS84Er2JTM9MKisbGyptEJRM4FQgQZedijQKs0F5x1AY03FGAfoeN3VDLDakfu_2SmGr3mRaEeXDA6D9hjm1IKUHGSjFvDuAi6GaNspulHHc_t_SPULmF1eEw |
ContentType | Journal Article |
DBID | CGR CUY CVF ECM EIF NPM 7X8 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
DatabaseTitleList | MEDLINE - Academic MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EndPage | 199 |
ExternalDocumentID | 16951852 |
Genre | Journal Article Comparative Study |
GroupedDBID | --- .1- .FO 0R~ 0SF 1P~ 4.4 457 53G 5VS 6I. AACTN AAEDT AAEDW AAFTH AAIKJ AALRI AAXUO ABMAC ABXHO ACGFS ADBBV ADEZE ADVLN AENEX AEVXI AEXQZ AFCTW AFJKZ AFRHN AFTJW AGHFR AITUG AJUYK AKRWK ALMA_UNASSIGNED_HOLDINGS AMRAJ APOWU AZFZN BAWUL BCNDV C1A CGR CUY CVF DIK EBS ECM EIF EJD F5P FDB GROUPED_DOAJ GX1 HZ~ IPNFZ IXB M41 M~E NCXOZ NPM O9- OG- OR0 P6G RIG RNS ROL RPM RSC SCD SSZ TR2 Z5R 7X8 |
ID | FETCH-LOGICAL-p542-298f10cf6063d87d19a9e5405e636a621be5ed9a2522b667dc300266b24b406e3 |
ISSN | 1808-8694 |
IngestDate | Sat Aug 17 02:14:09 EDT 2024 Sat Sep 28 07:50:35 EDT 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 2 |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-p542-298f10cf6063d87d19a9e5405e636a621be5ed9a2522b667dc300266b24b406e3 |
Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
PMID | 16951852 |
PQID | 68826879 |
PQPubID | 23479 |
PageCount | 5 |
ParticipantIDs | proquest_miscellaneous_68826879 pubmed_primary_16951852 |
PublicationCentury | 2000 |
PublicationDate | 2006 Mar-Apr 20060301 |
PublicationDateYYYYMMDD | 2006-03-01 |
PublicationDate_xml | – month: 03 year: 2006 text: 2006 Mar-Apr |
PublicationDecade | 2000 |
PublicationPlace | Brazil |
PublicationPlace_xml | – name: Brazil |
PublicationTitle | Brazilian journal of otorhinolaryngology |
PublicationTitleAlternate | Braz J Otorhinolaryngol |
PublicationYear | 2006 |
SSID | ssj0067075 |
Score | 1.6765164 |
Snippet | The aim of this study was to evaluate the bone formation in surgically created defects of rabbit mandibles by synthetic hydroxyapatite of calcium compared to... AIMThe aim of this study was to evaluate the bone formation in surgically created defects of rabbit mandibles by synthetic hydroxyapatite of calcium compared... |
SourceID | proquest pubmed |
SourceType | Aggregation Database Index Database |
StartPage | 195 |
SubjectTerms | Animals Bone Substitutes - therapeutic use Disease Models, Animal Hydroxyapatites - therapeutic use Intestinal Mucosa - transplantation Intestine, Small - transplantation Mandibular Injuries - surgery Osseointegration - physiology Osteogenesis - physiology Rats Rats, Inbred WF |
Title | Defect repair in rat mandible with hydroxyapatite cement compared to small intestine submucosa |
URI | https://www.ncbi.nlm.nih.gov/pubmed/16951852 https://search.proquest.com/docview/68826879 |
Volume | 72 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnZ3La9tAEIcXJ4fSS2nTV_pI9tBbUbFeu6tj0iakwUkPVsCnit3VuhYkUpDlQvzXd0YjKXZp6eMizIJs0CfvzuM3M4y9iyKjTazAN3GB86JQSs_kvvBsMtdRPk6MM1jvfHEpzq6i81k8G40mG6qlVWM-2PUv60r-hyqsAVeskv0HssOXwgJ8Br5wBcJw_SvGn1zberiGI6Wo28oUcPdvsFAF66HaEOviLkehikbhdOPe2zYaeK88B8tzeYPZaWwbAf92MDmXcEKijF1v5XtrvS7aiMhGq4kK_PVFUaJzfFd-24rPTytraXYXKiYpG69JjbQeIgCoMqK47rS4_k6CMJLb1lVJiagJ3np8ZIvh9JhqGvM-XbjiWv8ctOhVW90-q8bKU4LmG_cbsQw2XrhgY1f1aQ5nd0D7NFFpu3f25Zfs9GoyydKTWbrDdkIf5Z2fZ8f9qSwkNV0efvj3HkVrWaSP2aPOJeBHxPcJG7lyjz246EQPT9lXwswJMy9KDph5j5kjZr6NmRNm3mPmTcVbzHzAzAfMz1h6epJ-PPO6sRjebYy1VIma-2M7B88zzJXM_UQnDu1uJ0KhReAbF7s80QFY1kYImdsQHW1hgsiA9ebC52y3rEr3knElQmxpJ4zSeaTDsQ4jLZWOJCzFfm732WH_jDLYdTCVpEtXrZaZAMdMKJnssxf06LJbao6S-QJsdhUHr_5472v28P7VeMN2m3rl3oKF15iDFt0P3AdcYQ |
link.rule.ids | 315,786,790 |
linkProvider | Elsevier |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Defect+repair+in+rat+mandible+with+hydroxyapatite+cement+compared+to+small+intestine+submucosa&rft.jtitle=Brazilian+journal+of+otorhinolaryngology&rft.au=Soccol%2C+Andr%C3%A9a+Thomaz&rft.au=Bettega%2C+Silvio&rft.au=Noronha%2C+L%C3%BAcia&rft.au=Sass%2C+Sheila&rft.date=2006-03-01&rft.issn=1808-8694&rft.volume=72&rft.issue=2&rft.spage=195&rft.epage=199&rft.externalDBID=NO_FULL_TEXT |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1808-8694&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1808-8694&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1808-8694&client=summon |