Delayed response to rituximab of cold agglutinin haemolytic disease

• Published in: Anales de medicina interna (Madrid, Spain : 1984) Vol. 23; no. 5; pp. 224 - 228
• Main Authors: Calvo-Villas, J M, Cuesta Tovar, J, Carreter de Granda, E, Sicilia Guillén, F
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.05.2006
• Subjects: Anemia, Hemolytic, Autoimmune - drug therapy; Antibodies, Monoclonal - therapeutic use; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20 - immunology; Humans; Immunologic Factors - therapeutic use; Male; Middle Aged; Rituximab; Time Factors

The anti-CD20 monoclonal antibody rituximab has shown benefit in some patients diagnosed of severe cold agglutinin disease. Here we report our experience with rituximab in a patient with chronic haemolysis due to refractory cold agglutinin disease. An increase in the haemoglobin level was observed s...