The prognosis and control of the efficacy of heparin therapy in patients with diabetic glomerulosclerosis

• Published in: Klinicheskaia meditsina Vol. 74; no. 2; p. 32
• Main Authors: Pyrig, L A, Lapchinskaia, I I, Belitskaia, G A, Lezhen, T I, Iakovenko, A M, Ishchenko, V M, Fedorova, N E
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 1996
• Subjects: Adult; Diabetes Mellitus, Type 1 - blood; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 1 - drug therapy; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - drug therapy; Diabetic Nephropathies - blood; Diabetic Nephropathies - drug therapy; Drug Evaluation; Female; Glomerulosclerosis, Focal Segmental - blood; Glomerulosclerosis, Focal Segmental - drug therapy; Hemostasis - drug effects; Heparin - therapeutic use; Humans; Male; Middle Aged; Prognosis; Time Factors

3-week heparin treatment (25000 U/day) of 38 patients with diabetic glomerulosclerosis (DGS) produced positive results in 31 of them, was ineffective in 5 patients and induced complications in 2 cases. Prognostic criteria of heparin treatment efficacy basing on hemostatic changes on day 7 have been...