Haemolysis as initial sign of Clostridium perfringens septicaemia in newborn (author's transl)

Cases of Clostridium perfringens, septicaemia are subject to a very gloomy prognosis in adults. This applies likewise to the rare cases reported in paediatric literature. The present report describes the fatal case of a newborn with Clostridium perfringens septicaemia. The principal sign was a sever...

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Bibliographic Details
Published inKlinische Pädiatrie Vol. 193; no. 5; p. 398
Main Authors Töllner, U, Pohlandt, F, Vanek, E, Kohne, E, Kleihauer, E
Format Journal Article
LanguageGerman
Published Germany 01.09.1981
Subjects
Anemia, Hemolytic - etiology
Anemia, Hemolytic - therapy
Clostridium Infections - diagnosis
Exchange Transfusion, Whole Blood
Humans
Infant, Newborn
Sepsis - diagnosis
Sepsis - microbiology
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Summary:Cases of Clostridium perfringens, septicaemia are subject to a very gloomy prognosis in adults. This applies likewise to the rare cases reported in paediatric literature. The present report describes the fatal case of a newborn with Clostridium perfringens septicaemia. The principal sign was a severe haemolysis which failed to respond to blood exchange transfusions and antibiotic treatment. The characteristic changes of colour of the skin usually observed in septicaemia of newborn had probably been masked for some time by the reddish discolouration caused by the haemolysis, so that diagnosis was established at a late stage only.
ISSN:0300-8630
DOI:10.1055/s-2008-1034508