Effect of lipophilic derivatives of a divinyl ether-maleic anhydride copolymer on immunocompetent cells

• Published in: Voprosy meditsinskoi khimii Vol. 41; no. 6; p. 50
• Main Authors: Sukhin, G M, Pecherskikh, E V, Sarantseva, O S, Gorshkova, M Iu, Stotskaia, L L
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.11.1995
• Subjects: Animals; Antibody Formation - drug effects; B-Lymphocytes - drug effects; B-Lymphocytes - immunology; Immunity, Cellular - drug effects; Maleic Anhydrides - chemistry; Maleic Anhydrides - pharmacology; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Polymers; T-Lymphocytes - drug effects; T-Lymphocytes - immunology; Vinyl Compounds - chemistry; Vinyl Compounds - pharmacology

A series of lipophilic derivatives of the copolymer divinyl ether with maleic anhydride were synthesized and tested for their effects on immunocompetent cells. Increases in the length of a hydrophobic moiety and its quantity in the polymer chain of the agent were demonstrated to substantially modify...