Effect of lipophilic derivatives of a divinyl ether-maleic anhydride copolymer on immunocompetent cells

A series of lipophilic derivatives of the copolymer divinyl ether with maleic anhydride were synthesized and tested for their effects on immunocompetent cells. Increases in the length of a hydrophobic moiety and its quantity in the polymer chain of the agent were demonstrated to substantially modify...

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Published inVoprosy meditsinskoi khimii Vol. 41; no. 6; p. 50
Main Authors Sukhin, G M, Pecherskikh, E V, Sarantseva, O S, Gorshkova, M Iu, Stotskaia, L L
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.1995
Subjects
Animals
Antibody Formation - drug effects
B-Lymphocytes - drug effects
B-Lymphocytes - immunology
Immunity, Cellular - drug effects
Maleic Anhydrides - chemistry
Maleic Anhydrides - pharmacology
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Polymers
T-Lymphocytes - drug effects
T-Lymphocytes - immunology
Vinyl Compounds - chemistry
Vinyl Compounds - pharmacology
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Abstract A series of lipophilic derivatives of the copolymer divinyl ether with maleic anhydride were synthesized and tested for their effects on immunocompetent cells. Increases in the length of a hydrophobic moiety and its quantity in the polymer chain of the agent were demonstrated to substantially modify the factors of animals' humoral and cell-mediated immunity. This phenomena is well associated with the examined superficial qualities of solutions of the agents and their mycelium forming capacity.
AbstractList A series of lipophilic derivatives of the copolymer divinyl ether with maleic anhydride were synthesized and tested for their effects on immunocompetent cells. Increases in the length of a hydrophobic moiety and its quantity in the polymer chain of the agent were demonstrated to substantially modify the factors of animals' humoral and cell-mediated immunity. This phenomena is well associated with the examined superficial qualities of solutions of the agents and their mycelium forming capacity.
Author Stotskaia, L L
Sarantseva, O S
Pecherskikh, E V
Gorshkova, M Iu
Sukhin, G M
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DocumentTitleAlternate Vliianie lipofil'nykh proizvodnykh sopolimera divinilovogo éfira s maleinovym angidridom na immunokompetentnye kletki
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Snippet A series of lipophilic derivatives of the copolymer divinyl ether with maleic anhydride were synthesized and tested for their effects on immunocompetent cells....
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StartPage 50
SubjectTerms Animals
Antibody Formation - drug effects
B-Lymphocytes - drug effects
B-Lymphocytes - immunology
Immunity, Cellular - drug effects
Maleic Anhydrides - chemistry
Maleic Anhydrides - pharmacology
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Polymers
T-Lymphocytes - drug effects
T-Lymphocytes - immunology
Vinyl Compounds - chemistry
Vinyl Compounds - pharmacology
Title Effect of lipophilic derivatives of a divinyl ether-maleic anhydride copolymer on immunocompetent cells
URI https://www.ncbi.nlm.nih.gov/pubmed/8619305
Volume 41
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