Prophylactic administration of Claforan in patients with premature loss of amniotic fluid

The authors compared two groups of pregnant women with early loss of amniotic fluid. In the first group Claforan was administered, 3 x 1 g by the i.m. route, and in the second group Ampicillin, 3 x 1 g by the i.m. route. The data were recorded in a special protocol and were divided into three groups...

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Bibliographic Details
Published inCeskoslovenska gynekologie Vol. 57; no. 7; p. 321
Main Authors Horký, P, Matusková, D, Roztocil, A, Klimecká, K, Pilka, L
Format Journal Article
LanguageCzech
Published Czech Republic 01.09.1992
Subjects
Adult
Ampicillin - administration & dosage
Bacterial Infections - etiology
Bacterial Infections - prevention & control
Cefotaxime - administration & dosage
Female
Fetal Diseases - etiology
Fetal Diseases - prevention & control
Fetal Membranes, Premature Rupture - complications
Humans
Infant, Newborn
Pregnancy
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Summary:The authors compared two groups of pregnant women with early loss of amniotic fluid. In the first group Claforan was administered, 3 x 1 g by the i.m. route, and in the second group Ampicillin, 3 x 1 g by the i.m. route. The data were recorded in a special protocol and were divided into three groups: 1. patient before delivery, 2. patient during puerperium, 3. neonate. From the results two conclusions were drawn: 1. The authors did not detect any reasons why antibiotics should not be administered prophylactically in case of premature loss of amniotic fluid. 2. The main differences between the compared groups were found in neonates where after administration of Claforan there was a substantially lower incidence of positive bacterial cultures than after Ampicillin and there was also a lower incidence of RDS II and adnatal infections.
ISSN:0374-6852