Recombinant human erythropoietin in the treatment of the anemia of multiple myeloma with kidney failure

A patient with advanced multiple myeloma (MM) and renal failure presented a severe chronic anemia requiring frequent blood transfusions. Treatment with recombinant human erythropoietin (rHuEPO) led to a rapid improvement of anemia, and further blood transfusions were not required. Pathophysiological...

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Bibliographic Details
Published inAnales de medicina interna (Madrid, Spain : 1984) Vol. 12; no. 4; p. 187
Main Authors Arenas Gracia, M, Abad Gosálvez, A, Colomina Avilés, J, Pascual Pérez, R, Ferriz Moreno, P
Format Journal Article
LanguageSpanish
Published Spain 01.04.1995
Subjects
Aged
Anemia - drug therapy
Anemia - etiology
Chronic Disease
Combined Modality Therapy
Erythropoietin - therapeutic use
Fatal Outcome
Female
Humans
Immunoglobulin kappa-Chains
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - therapy
Multiple Myeloma - complications
Multiple Myeloma - therapy
Recombinant Proteins - therapeutic use
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Summary:A patient with advanced multiple myeloma (MM) and renal failure presented a severe chronic anemia requiring frequent blood transfusions. Treatment with recombinant human erythropoietin (rHuEPO) led to a rapid improvement of anemia, and further blood transfusions were not required. Pathophysiological studies about the erythropoiesis in patients with MM and trials with rHuEPO in myeloma-associated anemia are commented.
ISSN:0212-7199