Urinary excretion of mutagens and cisplatin among the nursing staff at a medical oncology department exposed to cytostatic drugs

• Published in: Medicina del lavoro Vol. 80; no. 5; p. 412
• Main Authors: Clonfero, E, Granella, M, Gori, G P, Venier, P, Levis, A G, Morandi, P, Bartolucci, G B, Saia, B
• Format: Journal Article
• Language: Italian
• Published: Italy 01.09.1989
• Subjects: Antineoplastic Agents - urine; Cancer Care Facilities; Cisplatin - urine; Cyclophosphamide - urine; Environmental Exposure; Humans; Mutagenicity Tests; Nursing Staff; Smoking - metabolism

Exposure to cytostatic drugs was assessed in a group of 9 nurses employed in a hospital cancer therapy department by measuring the post-shift levels of urinary mutagens and cis-platinum. A slight but significant increase in urinary mutagenic activity compared to 11 controls was observed in the non-s...