Continuous perfusion of low doses of insulin in severe diabetic decompensation (author's transl)

Twenty one episodes of severe uncontrolled diabetes, most of them with ketoacidosis, were treated at a Medical Intensive Care Unit with fluid and electrolyte replacement and continuous perfusion of low doses of insulin. The overall results of this therapeutic approach were a progressive and gradual...

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Bibliographic Details
Published inMedicina clínica Vol. 76; no. 3; p. 117
Main Authors Herrera Carranza, M, Rubio Quiñones, J, Pou Dimaio, J J, Leal del Ojo González, J, Medina Sierra, J C, Tejedor Fernández, M, Garcĩa Castilla, J M
Format Journal Article
LanguageSpanish
Published Spain 10.02.1981
Subjects
Adolescent
Adult
Aged
Blood Glucose
Child
Diabetes Mellitus - drug therapy
Diabetic Ketoacidosis - drug therapy
Female
Humans
Hydrogen-Ion Concentration
Hyperglycemic Hyperosmolar Nonketotic Coma - drug therapy
Insulin - administration & dosage
Male
Middle Aged
Potassium - blood
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Summary:Twenty one episodes of severe uncontrolled diabetes, most of them with ketoacidosis, were treated at a Medical Intensive Care Unit with fluid and electrolyte replacement and continuous perfusion of low doses of insulin. The overall results of this therapeutic approach were a progressive and gradual return to normality of all biochemical parameters with a fall of serum glucose levels and no hypoglycemic or hypokalemic accidents. Based on this study and on a review of the literature, an updated protocol for therapy of diabetic ketoacidosis is proposed.
ISSN:0025-7753