Immobilization of myocardial tropomyosin

Immobilized granulated myocardial tropomyosin with magnetic properties of prolonged period of storage was obtained. Tropomyosin inclusion into granules emulsion polymerisation is 89.5%. The largest amount of protein is extracted from granules after 2-3 days, and later this process is slowed down. St...

Full description

Saved in:
Bibliographic Details
Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 109; no. 4; p. 330
Main Authors Gontar', I P, Sycheva, G F, Podzolkov, V P, Emel'ianova, O I, Nikitin, M V, Zborovskaia, I A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.04.1990
Subjects
Antigens
Biological Products - isolation & purification
Biological Products - pharmacology
Drug Stability
Drug Storage
Humans
Immunosorbent Techniques
Immunosorbents
Myocardium
Rheumatic Diseases - diagnosis
Rheumatic Diseases - immunology
Temperature
Time Factors
Tropomyosin - isolation & purification
Tropomyosin - pharmacology
Online AccessGet more information

Cover

More Information
Summary:Immobilized granulated myocardial tropomyosin with magnetic properties of prolonged period of storage was obtained. Tropomyosin inclusion into granules emulsion polymerisation is 89.5%. The largest amount of protein is extracted from granules after 2-3 days, and later this process is slowed down. Studying temperature effect, the maximum protein output was also shown to be reached after 2-3 days and depends on the temperature. Processing of granules, containing tropomyosin, with a solution with high concentration of hydrogen ions, the same results were obtained as under the influence of temperature. The use of 3 mol potassium rodanide did not show the peak of protein washing out of granules.
ISSN:0365-9615