The concentration of 17-OHKS and glucose in the blood during the insulin test in patients with hypothalamo-hypophyseal diseases

A study was made of the hypothalamo-hypophysio-adrenal gland interrelations during the insulin test in patients with Itsenko-Cushing disease, dyspituitrism of the puberto-juvenile period and diencephalic syndrome. The majority of the patients with Itsenko-Cushing disease displayed a reduction of ins...

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Bibliographic Details
Published inProblemy ėndokrinologii Vol. 21; no. 6; p. 36
Main Authors Marova, E I, Arapova, S D
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.1975
Subjects
17-Ketosteroids - blood
Adolescent
Adult
Brain Diseases - blood
Cushing Syndrome - blood
Diencephalon
Female
Humans
Insulin
Male
Middle Aged
Pituitary Diseases - blood
Puberty
Syndrome
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Summary:A study was made of the hypothalamo-hypophysio-adrenal gland interrelations during the insulin test in patients with Itsenko-Cushing disease, dyspituitrism of the puberto-juvenile period and diencephalic syndrome. The majority of the patients with Itsenko-Cushing disease displayed a reduction of insulin sensitivity, this being expressed in a delayed fall of the glucose level during the insulin test and the absence of any increase in the blood 17-OCS. An increased reaction of the hypothalamo-hypophysio-adrenal system to insulin hypoglycemia was observed in the patients with dyspituitrim of the puberto-juvenile period. A normal reaction to the insulin test was seen in all the patients with the diencephalic syndrome. The data obtained could be used in differential diagnosis between these diseases and Itsenko-Cushing disease.
ISSN:0375-9660