Spleen and lymph node changes in rats irradiated with X-rays and treated with testosterone
The authors have studied the effect of testosterone administration in male adult Wistar rats irradiated with a single total dose of 800 r X-rays. The results obtained show that testosterone exerts a double radioprotective action. This hormone prevents both the occurrence of the senile type spleen an...
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Published in | Morphologie et embryologie Vol. 25; no. 2; p. 163 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Romania
01.04.1979
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Abstract | The authors have studied the effect of testosterone administration in male adult Wistar rats irradiated with a single total dose of 800 r X-rays. The results obtained show that testosterone exerts a double radioprotective action. This hormone prevents both the occurrence of the senile type spleen and lymph node changes and the depression of the colloidopexic capacity of the hepatosplenic macrophages. At the same time, these results suggest that testosterone induces hyperplasia of the lymphocytic elements, particularly of T lymphocytes. |
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AbstractList | The authors have studied the effect of testosterone administration in male adult Wistar rats irradiated with a single total dose of 800 r X-rays. The results obtained show that testosterone exerts a double radioprotective action. This hormone prevents both the occurrence of the senile type spleen and lymph node changes and the depression of the colloidopexic capacity of the hepatosplenic macrophages. At the same time, these results suggest that testosterone induces hyperplasia of the lymphocytic elements, particularly of T lymphocytes. |
Author | Mureşan, D Papilian, V V Gocan, M E Olinic, A Carpen, E Radu-Toader, M |
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Snippet | The authors have studied the effect of testosterone administration in male adult Wistar rats irradiated with a single total dose of 800 r X-rays. The results... |
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SubjectTerms | Aging Animals Hyperplasia - pathology Lymph Nodes - metabolism Lymph Nodes - pathology Macrophages - pathology Male Radiation Chimera Rats Spleen - metabolism Spleen - pathology Testosterone - pharmacology |
Title | Spleen and lymph node changes in rats irradiated with X-rays and treated with testosterone |
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