A novel P2Y(12) adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models - Wang, Yi-Xin; Vincelette, Jon; da Cunha, Valdeci; Martin-McNulty, Baby; Mallari, Cornell; Fitch, Richard M; Alexander, Serene; Islam, Imadul; Buckman, Brad O; Yuan, Shendong; Post, Joseph M; Subramanyam, Babu; et al. (Thrombosis and haemostasis, 2007)
Keywords: Animals; Arteriovenous Shunt, Surgical; Carotid Artery Injuries - drug therapy; Clopidogrel; Disease Models, Animal; Dogs; In Vitro Techniques; Male; Membrane Proteins - antagonists & inhibitors; Molecular Structure; Platelet Aggregation - drug effects; Platelet Aggregation Inhibitors - blood; Platelet Aggregation Inhibitors - chemistry; Platelet Aggregation Inhibitors - pharmacology; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thrombosis - prevention & control; Ticlopidine - analogs & derivatives; Ticlopidine - pharmacology