Graph analysis of epileptogenic networks in human partial epilepsy

• Published in: Epilepsia (Copenhagen) Vol. 52; no. 1; pp. 84 - 93
• Main Authors: Wilke, Christopher, Worrell, Gregory, He, Bin
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.01.2011; Wiley-Blackwell; Wiley Subscription Services, Inc
• Subjects: Action Potentials - physiology; Anticonvulsants. Antiepileptics. Antiparkinson agents; Biological and medical sciences; Brain Mapping - methods; Brain Mapping - statistics & numerical data; Cortex; Electrocorticography; Electroencephalography - methods; Electroencephalography - statistics & numerical data; Epilepsies, Partial - diagnosis; Epilepsies, Partial - physiopathology; Epilepsy; Firing pattern; Graph analysis; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Manganese; Medical research; Medical sciences; Neocortex - physiopathology; Nerve Net - physiopathology; Nervous system (semeiology, syndromes); Neurology; Neuropharmacology; Nodes; Pharmacology. Drug treatments; Seizure; Source localization; Therapeutic applications; Human; Nervous system diseases; Graph analysis; Epilepsy; Electrophysiology; Cerebral disorder; Convulsion; Source localization; Central nervous system disease; Seizure; Neurological disorder; Localization; Electrocorticography

Summary Purpose:  The current gold standard for the localization of the cortical regions responsible for the initiation and propagation of the ictal activity is through the use of invasive electrocorticography (ECoG). This method is utilized to guide surgical intervention in cases of medically intra...