Structure of an Agonist-Bound Human A2A Adenosine Receptor - FEI XU; HUIXIAN WU; KATRITCH, Vsevolod; GYE WON HAN; JACOBSON, Kenneth A; GAO, Zhan-Guo; CHEREZOV, Vadim; STEVENS, Raymond C (Science (American Association for the Advancement of Science), 2011)
Keywords: Adenosine - analogs & derivatives; Adenosine - chemistry; Adenosine - metabolism; Adenosine A2 Receptor Agonists - chemistry; Adenosine A2 Receptor Agonists - metabolism; Adenosines; agonists; Binding Sites; Biological and medical sciences; Cell physiology; Cellular biology; Crystal structure; Crystalline structure; Crystallography, X-Ray; Displays; Fundamental and applied biological sciences. Psychology; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Molecular and cellular biology; Molecular biology; Molecular biophysics; Movement; opsin; Opsins - chemistry; Opsins - metabolism; Protein Conformation; Protein Structure, Secondary; Proteins; purinergic receptors; Receptor, Adenosine A2A - chemistry; Receptor, Adenosine A2A - metabolism; Receptors; Rhodopsin - chemistry; Rhodopsin - metabolism; Signal transduction; Structure in molecular biology; Surface chemistry; surface proteins; Tilt; Triazines - chemistry; Triazines - metabolism; Triazoles - chemistry; Triazoles - metabolism; Shift; Human; Signal transduction; Agonist; Regulation(control); G protein coupled receptor; Activation; Antagonist; Cell surface; Biological receptor; Crystalline structure