Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16 - Wang, Pei‐Hui; Ye, Zi‐Wei; Deng, Jian‐Jun; Siu, Kam‐Leung; Gao, Wei‐Wei; Chaudhary, Vidyanath; Cheng, Yun; Fung, Sin‐Yee; Yuen, Kit‐San; Ho, Ting‐Hin; Chan, Ching‐Ping; Zhang, Yan; et al. (EMBO reports, 2018)
Keywords: Activation; AIM2; Animals; Autoimmune diseases; Cell Nucleus - genetics; Complex formation; Cytoplasm; DNA - genetics; DNA-Binding Proteins - antagonists & inhibitors; DNA-Binding Proteins - genetics; Double-stranded RNA; EMBO19; EMBO23; EMBO37; Gene Expression Regulation; Gene Knockdown Techniques; Homology; Human tissues; Humans; IFI16; inflammasome; Inflammasomes; Inflammasomes - genetics; Interferon; Interleukin-1beta - genetics; Interleukins; Intracellular Signaling Peptides and Proteins - genetics; Leukocytes; Mice; Nuclear Proteins - genetics; Phosphoproteins - genetics; Protein Isoforms - genetics; Pyrin protein; RNA, Double-Stranded - genetics; RNA, Messenger - genetics; transcript isoform; Transcription; Viruses; AIM2; IFI16; transcript isoform; inflammasome