Accelerated 3D metabolite T1 mapping of the brain using variable‐flip‐angle SPICE

• Published in: Magnetic resonance in medicine Vol. 92; no. 4; pp. 1310 - 1322
• Main Authors: Zhao, Yibo, Li, Yudu, Guo, Rong, Jin, Wen, Sutton, Brad, Ma, Chao, El Fakhri, Georges, Li, Yao, Luo, Jie, Liang, Zhi‐Pei
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.10.2024
• Subjects: Brain; Brain mapping; Data acquisition; Data processing; FID MRSI; Imaging; In vivo methods and tests; Information processing; Lipids; low‐rank tensor modeling; Mapping; metabolite T1 mapping; Metabolites; Neuroimaging; Signal processing; Signal quality; Subspaces; Substantia alba; Substantia grisea; Tensors; variable flip angle

Purpose To develop a practical method to enable 3D T1 mapping of brain metabolites. Theory and Methods Due to the high dimensionality of the imaging problem underlying metabolite T1 mapping, measurement of metabolite T1 values has been currently limited to a single voxel or slice. This work achieved...