Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure: Refining the Gut Hypothesis - TANG, W. H. Wilson; ZENENG WANG; YIYING FAN; LEVISON, Bruce; HAZEN, Jennie E; DONAHUE, Lillian M; YUPING WU; HAZEN, Stanley L (Journal of the American College of Cardiology, 2014)
Keywords: Aged; Biological and medical sciences; Biomarkers - blood; Cardiology. Vascular system; Female; Follow-Up Studies; Heart; Heart Failure - blood; Heart Failure - mortality; Heart failure, cardiogenic pulmonary edema, cardiac enlargement; Humans; Intestines - metabolism; Intestines - microbiology; Kaplan-Meier Estimate; Male; Mass Spectrometry; Medical sciences; Methylamines - blood; Microbiota; Middle Aged; Ohio - epidemiology; Prognosis; Prospective Studies; Risk Assessment - methods; Survival Rate - trends; Time Factors; Ohio; Human; Heart failure; Digestive system; Metabolite; Gut; Patient; Oxides; Cardiovascular disease; Hypothesis; Heart disease; Predictive value; Level; Circulatory system; Cardiology; TMAO; mortality; intestinal microbiota; cardiorenal; C-reactive protein