Ubiquitination and Degradation of the Zebrafish Paired‐Like Homeobox Protein Vsx‐1

• Published in: Journal of neurochemistry Vol. 75; no. 1; pp. 48 - 55
• Main Authors: Kurtzman, Aaron L., Gregori, Luisa, Haas, Arthur L., Schechter, Nisson
• Format: Journal Article
• Language: English
• Published: Oxford UK Blackwell Science Ltd 01.07.2000; Blackwell
• Subjects: 26S proteasome; Adenosine Triphosphatases - metabolism; Animals; Biological and medical sciences; Bipolar cells; Chx10; COS Cells; Cysteine Endopeptidases - metabolism; Danio rerio; Electrophoresis, Polyacrylamide Gel; Eye and associated structures. Visual pathways and centers. Vision; Eye Proteins - genetics; Eye Proteins - metabolism; Freshwater; Fundamental and applied biological sciences. Psychology; Gene Expression; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; Multienzyme Complexes - metabolism; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Rabbits; Reticulocytes - metabolism; Retina; Retina - growth & development; Transfection; Ubiquitin; Ubiquitins - metabolism; Vertebrates: nervous system and sense organs; Vsx-1 gene; Zebrafish; Zebrafish Proteins; Ubiquitin; Bipolar neuron; Transcription factor Vsx1; Retina; Eye; Visual system; Vertebrata; Brachydanio rerio; Cell line; Pisces; Development; Differentiation; Homeobox sequence

: Vsx‐1 is a paired‐like : CVC homeobox protein dynamically expressed during zebrafish development. Previous results indicate that Vsx‐1 influences bipolar cell differentiation and maintenance of these cells in the adult retina. To understand the developmental regulation of this transcription factor...