Predicting progression of bladder urothelial carcinoma using microRNA expression

• Published in: BJU international Vol. 112; no. 7; pp. 1027 - 1034
• Main Authors: Rosenberg, Eran, Baniel, Jack, Spector, Yael, Faerman, Alexander, Meiri, Eti, Aharonov, Ranit, Margel, David, Goren, Yaron, Nativ, Ofer
• Format: Journal Article
• Language: English
• Published: Oxford Wiley-Blackwell 01.11.2013; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Biomarkers; Bladder cancer; cancer progression; Carcinoma, Transitional Cell - genetics; Carcinoma, Transitional Cell - pathology; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Medical sciences; MicroRNAs; MicroRNAs - biosynthesis; Middle Aged; molecular biomarkers; Multiple tumors. Solid tumors. Tumors in childhood (general aspects); Neoplasm Invasiveness; Nephrology. Urinary tract diseases; Patients; Prognosis; Tumors; Tumors of the urinary system; Urinary Bladder Neoplasms - genetics; Urinary Bladder Neoplasms - pathology; Urinary tract. Prostate gland; urothelial carcinoma; microRNAs; Nephrology; Urinary system disease; RNA interference; Prognosis; Micro RNA; Biological marker; Biological indicator; molecular biomarkers; Urinary tract disease; Malignant tumor; Transitional cell carcinoma; Baldder transitional cell carcinoma; Urology; Gene silencing; urothelial carcinoma; cancer progression; Tumor progression; Evolution; Bladder disease; Cancer

What's known on the subject? and What does the study add? Recurrence and progression prediction in urothelial cancer is currently based on clinical and pathological factors: tumour grade, tumour stage, number of lesions, tumour size, previous recurrence rate, and presence of concomitant carcino...