Correlation between PARP-1 Val762Ala polymorphism and the risk of lung cancer in a Chinese population

• Published in: Tumor biology Vol. 36; no. 1; p. 177
• Main Authors: Yu, Ping, Liu, Yun-Peng, Zhang, Jing-Dong, Qu, Xiu-Juan, Jin, Bo, Zhang, Ye
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 01.01.2015
• Subjects: Adenocarcinoma - genetics; Adult; Amino Acid Substitution; Carcinoma, Squamous Cell - genetics; Case-Control Studies; China; Correlation analysis; Female; Genetic Association Studies; Genetic Predisposition to Disease; Health risk assessment; Humans; Lung cancer; Lung Neoplasms - genetics; Male; Middle Aged; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases - genetics; Polymorphism; Polymorphism, Single Nucleotide; Population genetics; Sequence Analysis, DNA; Small Cell Lung Carcinoma - genetics; China

The aim of this study was to investigate the relationship of the PARP-1 Val762Ala (rs1136410 T>C) polymorphism and the risk of lung cancer. A population-based case-control study of 373 lung cancer patients and 360 healthy control subjects (individually matched on age and gender) in a Chinese popu...