Effect of Fasudil on remyelination following cuprizone‐induced demyelination

• Published in: CNS neuroscience & therapeutics Vol. 26; no. 1; pp. 76 - 89
• Main Authors: Wang, Jing, Sui, Ruo‐Xuan, Miao, Qiang, Wang, Qing, Song, Li‐Juan, Yu, Jie‐Zhong, Li, Yan‐Hua, Xiao, Bao‐Guo, Ma, Cun‐Gen
• Format: Journal Article
• Language: English
• Published: England John Wiley and Sons Inc 01.01.2020
• Subjects: cuprizone‐induced demyelination; Fasudil; Original; remyelination; Rho kinase; Rho kinase; cuprizone-induced demyelination; Fasudil; remyelination

Background Multiple sclerosis is characterized by demyelination/remyelination, neuroinflammation, and neurodegeneration. Cuprizone (CPZ)‐induced toxic demyelination is an experimental animal model commonly used to study demyelination and remyelination in the central nervous system. Fasudil is one of...