miRNA-based biomarkers, therapies, and resistance in Cancer

• Published in: International journal of biological sciences Vol. 16; no. 14; pp. 2628 - 2647
• Main Authors: He, Boxue, Zhao, Zhenyu, Cai, Qidong, Zhang, Yuqian, Zhang, Pengfei, Shi, Shuai, Xie, Hui, Peng, Xiong, Yin, Wei, Tao, Yongguang, Wang, Xiang
• Format: Journal Article
• Language: English
• Published: Australia Ivyspring International Publisher Pty Ltd 01.01.2020; Ivyspring International Publisher
• Subjects: Animals; Biomarkers; Biomarkers, Tumor - metabolism; Biosynthesis; Cancer; Cancer screening; Cognition; Cytoplasm; Drug Resistance, Neoplasm; Enzymes; Exports; Gene expression; Gene regulation; Genomes; Humans; Medical prognosis; MicroRNAs; MicroRNAs - biosynthesis; miRNA; Molecular Targeted Therapy; Neoplasms - metabolism; Neoplasms - therapy; Nucleotides; Patients; Prognosis; Proteins; Regulatory mechanisms (biology); Review; RNA polymerase; Transfer RNA; Tumors; Cancer therapy resistance; miRNA-based biomarkers; MicroRNAs; miRNA-based therapies; Cancer

MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in size, play important roles in gene regulation, and their dysregulation is implicated in human diseases including cancer. A variety of miRNAs could take roles in the cancer progression, participate in the process of tumor i...