Small-molecule–induced DNA damage identifies alternative DNA structures in human genes - Rodriguez, Raphaël; Miller, Kyle M; Forment, Josep V; Bradshaw, Charles R; Nikan, Mehran; Britton, Sébastien; Oelschlaegel, Tobias; Xhemalce, Blerta; Balasubramanian, Shankar; Jackson, Stephen P (Nature chemical biology, 2012)
Keywords: 631/337/1427; 631/92/555; 631/92/613; 692/699/67; Aminoquinolines - chemical synthesis; Aminoquinolines - chemistry; Aminoquinolines - pharmacology; Antineoplastic Agents - chemical synthesis; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Biochemical Engineering; Biochemistry; Bioorganic Chemistry; Breast cancer; Breast Neoplasms - genetics; Breast Neoplasms - pathology; Cell Biology; Cell Cycle - drug effects; Cell Proliferation - drug effects; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Chromatin; Deoxyribonucleic acid; DNA; DNA - chemistry; DNA - drug effects; DNA - genetics; DNA Damage; DNA structure; Drug Screening Assays, Antitumor; G-Quadruplexes - drug effects; Genetics; Genomes; genomics; Humans; Immunoprecipitation; Mammalian cells; Mammals; Molecular biology; Molecular Weight; Motility; Nucleotide sequence; Oncology; Pharmacology; Picolinic Acids - chemical synthesis; Picolinic Acids - chemistry; Picolinic Acids - pharmacology; Proto-Oncogene Mas; Proto-oncogenes; Src protein; Structure-Activity Relationship; Transcription; Tumor Cells, Cultured