Report on a cryotherapy service for women with cervical intraepithelial neoplasia in a district hospital in western Kenya

• Published in: African health sciences Vol. 11; no. 3; pp. 370 - 376
• Main Authors: Lewis, K D C, Sellors, J W, Dawa, A, Tsu, V D, Kidula, N A
• Format: Journal Article
• Language: English
• Published: Uganda Makerere Medical School 01.09.2011
• Subjects: Adult; Cervical cancer; Cervical Intraepithelial Neoplasia - diagnosis; Cervical Intraepithelial Neoplasia - surgery; Cervix Uteri - surgery; Cryosurgery; Female; Health and Medicine; Humans; Kenya; Medical Screening; Medical treatment; Non Communicable diseases; Research methodology; Statistical analysis; Studies; Treatment Outcome; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - surgery; Women; Kenya; precancerous conditions; cryotherapy; neoplasms; developing countries; uterine cervical neoplasms
• ISSN: 1680-6905; 1729-0503

In low-resource settings, cryotherapy can be cost-effective, affordable, and a first-line treatment for cervical intraepithelial neplasia (CIN) of any grade. To report the acceptability, safety and effectiveness of cryotherapy for women with cervical intraepithelial neoplasia (CIN) in Western Kenya. Visual inspection with acetic acid (VIA)-positive women and those suspected of having cervical cancer based on an initial evaluation at a primary health facility were referred to the district hospital for colposcopy and additional evaluation using visual inspection with Lugol's iodine (VILI) and/or visual inspection with acetic acid and magnification (VIAM). Cryotherapy was offered immediately to women diagnosed with appropriate CIN lesions based on colposcopy or after waiting for a confirmatory cervical biopsy and a follow up visit occurred one year later. Ninety one 91 women 30 to 39 years of age had CIN appropriate for cryotherapy. Approximately 36% (24/67) were due for their 1 year follow up visit and 20 of 24 (83.3%) attended. Complete data were available for 18 of 20 (90%) and 13 (72.2%) had no sign of CIN. No serious adverse events were reported 1 to 3 months after cryotherapy. All respondents reported that the treatment experience was acceptable. Cryotherapy was acceptable, safe and effective.