Seventy-Peak Kilovoltage High-Pitch Thoracic Aortic CT Angiography without ECG Gating: Evaluation of Image Quality and Radiation Dose
To assess the feasibility of 70-kVp high-pitch non-ECG-gated thoracic aortic computed tomography angiography (CTA) with 40-mL contrast agent compared to 100-kVp standard-pitch CTA with 60-mL contrast agent. Sixty-seven patients (51 men and 16 women; mean age, 55 ± 14 years) received non-ECG-gated ao...
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Published in | Academic radiology Vol. 22; no. 7; p. 890 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
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United States
01.07.2015
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Abstract | To assess the feasibility of 70-kVp high-pitch non-ECG-gated thoracic aortic computed tomography angiography (CTA) with 40-mL contrast agent compared to 100-kVp standard-pitch CTA with 60-mL contrast agent.
Sixty-seven patients (51 men and 16 women; mean age, 55 ± 14 years) received non-ECG-gated aortic CTA at 70 kVp, high pitch of 3.4, and 40-mL contrast agent (group A, n = 31) or CTA at 100-kVp, pitch of 1.2, and 60-mL contrast agent (group B, n = 36). Iterative reconstruction was used in all patients. For image quality assessment, CTA images were evaluated on a three-point scale and signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated and compared. Furthermore, computed tomography (CT) dose index was recorded.
Mean CT values and noise levels were higher in group A compared to group B (all P < .001), whereas SNR and CNR were lower than those in group B (all P < .001). Furthermore, the image quality of the aorta at the level of the diaphragm was lower in group A than that in group B (P < .05). However, image quality was graded as diagnostic in all patients, and motion artifacts of the aortic arch were significantly decreased in group A (P <.05). Interreader agreement was good or excellent for image quality assessment (k = 0.625-0.835). The 70-kVp CTA protocol, which allows dose reduction of 85%, was considered diagnostic in all instances by two readers.
Our proposed thoracic aortic CTA protocol provides diagnostic information with substantial reduction of both radiation and contrast agent doses compared to standard-pitch CTA at 100 kVp. |
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AbstractList | To assess the feasibility of 70-kVp high-pitch non-ECG-gated thoracic aortic computed tomography angiography (CTA) with 40-mL contrast agent compared to 100-kVp standard-pitch CTA with 60-mL contrast agent.
Sixty-seven patients (51 men and 16 women; mean age, 55 ± 14 years) received non-ECG-gated aortic CTA at 70 kVp, high pitch of 3.4, and 40-mL contrast agent (group A, n = 31) or CTA at 100-kVp, pitch of 1.2, and 60-mL contrast agent (group B, n = 36). Iterative reconstruction was used in all patients. For image quality assessment, CTA images were evaluated on a three-point scale and signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated and compared. Furthermore, computed tomography (CT) dose index was recorded.
Mean CT values and noise levels were higher in group A compared to group B (all P < .001), whereas SNR and CNR were lower than those in group B (all P < .001). Furthermore, the image quality of the aorta at the level of the diaphragm was lower in group A than that in group B (P < .05). However, image quality was graded as diagnostic in all patients, and motion artifacts of the aortic arch were significantly decreased in group A (P <.05). Interreader agreement was good or excellent for image quality assessment (k = 0.625-0.835). The 70-kVp CTA protocol, which allows dose reduction of 85%, was considered diagnostic in all instances by two readers.
Our proposed thoracic aortic CTA protocol provides diagnostic information with substantial reduction of both radiation and contrast agent doses compared to standard-pitch CTA at 100 kVp. |
Author | Schoepf, U Joseph Li, Xie Lu, Guang Ming Zhao, Yan E Tang, Chun Xiang Zhou, Chang Sheng Mangold, Stefanie Zhang, Long Jiang Felmly, Lloyd M Qi, Li |
Author_xml | – sequence: 1 givenname: Long Jiang surname: Zhang fullname: Zhang, Long Jiang organization: Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China – sequence: 2 givenname: Yan E surname: Zhao fullname: Zhao, Yan E organization: Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China – sequence: 3 givenname: U Joseph surname: Schoepf fullname: Schoepf, U Joseph organization: Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China; Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina – sequence: 4 givenname: Stefanie surname: Mangold fullname: Mangold, Stefanie organization: Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina – sequence: 5 givenname: Lloyd M surname: Felmly fullname: Felmly, Lloyd M organization: Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina – sequence: 6 givenname: Xie surname: Li fullname: Li, Xie organization: Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China – sequence: 7 givenname: Chun Xiang surname: Tang fullname: Tang, Chun Xiang organization: Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China – sequence: 8 givenname: Chang Sheng surname: Zhou fullname: Zhou, Chang Sheng organization: Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China – sequence: 9 givenname: Li surname: Qi fullname: Qi, Li organization: Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China – sequence: 10 givenname: Guang Ming surname: Lu fullname: Lu, Guang Ming email: cjr.luguangming@vip.163.com organization: Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China. Electronic address: cjr.luguangming@vip.163.com |
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Keywords | Aorta radiation dose X-ray computed tomography high pitch angiography contrast agent |
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SubjectTerms | Aorta, Thoracic - diagnostic imaging Aortic Diseases - diagnostic imaging Aortography - methods Cardiac-Gated Imaging Techniques Contrast Media - administration & dosage Feasibility Studies Female Humans Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Iohexol - administration & dosage Iohexol - analogs & derivatives Male Middle Aged Radiation Dosage Radiation Protection - methods Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed - methods |
Title | Seventy-Peak Kilovoltage High-Pitch Thoracic Aortic CT Angiography without ECG Gating: Evaluation of Image Quality and Radiation Dose |
URI | https://www.ncbi.nlm.nih.gov/pubmed/25872860 |
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