PTPN3 acts as a tumor suppressor and boosts TGF‐β signaling independent of its phosphatase activity - Yuan, Bo; Liu, Jinquan; Cao, Jin; Yu, Yi; Zhang, Hanchenxi; Wang, Fei; Zhu, Yezhang; Xiao, Mu; Liu, Sisi; Ye, Youqiong; Ma, Le; Xu, Dewei; et al. (The EMBO journal, 2019)
Keywords: Amino acid substitution; Amino acids; Arginine; Cancer; Cholangiocarcinoma; EMBO03; EMBO31; EMBO37; Hepatocellular carcinoma; Kinases; Leucine; Mutation; Pathogenesis; Phosphatase; Phosphorylation; Physiological responses; Physiology; Protein-tyrosine-phosphatase; Signaling; Smad protein; Smurf2; TGF‐β signaling; Transcription; Tumor suppressor genes; Tumors; Tyrosine; TβRI; TβRI; phosphatase; Smurf2; cholangiocarcinoma; TGF‐β signaling