Quantitative distribution of a panel of circulating mRNA in preeclampsia versus controls

• Published in: Prenatal diagnosis Vol. 26; no. 12; pp. 1115 - 1120
• Main Authors: Farina, Antonio, Sekizawa, Akihiko, Purwosunu, Yuditiya, Rizzo, Nicola, Banzola, Irina, Concu, Manuela, Morano, Danila, Giommi, Federica, Bevini, Maurizio, Mabrook, Mohamad, Carinci, Paolo, Okai, Takashi
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.12.2006; Wiley
• Subjects: Biological and medical sciences; Biomarkers - blood; Case-Control Studies; circulating mRNA; Diseases of mother, fetus and pregnancy; Female; Fetal Growth Retardation - genetics; Gestational Age; Gynecology. Andrology. Obstetrics; Humans; Inhibins - genetics; Kisspeptins; Management. Prenatal diagnosis; Medical sciences; molecular markers; multivariable screening; P-Selectin - genetics; Placental Lactogen - genetics; Plasminogen Activator Inhibitor 1 - genetics; Pre-Eclampsia - genetics; preeclampsia; Pregnancy; Pregnancy Trimester, Third; Pregnancy-Associated Plasma Protein-A - genetics; Pregnancy. Fetus. Placenta; real‐time PCR; Receptors, Vascular Endothelial Growth Factor - genetics; Reference Values; RNA, Messenger - blood; Tumor Suppressor Proteins - genetics; multivariable screening; Pregnancy disorders; Genetic marker; Prenatal Diagnosis; Molecular marker; real-time PCR; Medical screening; Real time; circulating mRNA; Pregnancy toxemia; Polymerase chain reaction; Messenger RNA; Preeclampsia; Distribution; Molecular biology; molecular markers; Comparative study; Quantitative analysis

Objective The aim of this study was to evaluate whether the quantitative distribution of a panel of circulating mRNAs from maternal whole blood of normal pregnancies is statistically different from those complicated with preeclampsia (PE) with or without intrauterine growth restriction (IUGR). Metho...