Metal‐Free, Hindered, Regioselective Access to Multifunctional Groups Diarylamines via SNAr Substitution of P‐Nitroso Aromatic Methyl Ether by Arylamines

• Published in: Chemistry : a European journal Vol. 30; no. 11
• Main Authors: Zou, Shuliang, Zhang, Yazhou, Wu, Qin, Zhao, Tianming, Li, Yutao, Liu, Bing, Ma, Xianguo
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 21.02.2024; Wiley Subscription Services, Inc
• Subjects: amination; Amines; Charge transfer; Chemistry; Chemistry, Multidisciplinary; Functional groups; hindered; intermolecular nucleophilic aromatic substitution; nitroso arenes; Organic compounds; Physical Sciences; regioselective; Regioselectivity; Science & Technology; Substitution reactions; Substrates; ACTIVATION; nitroso arenes; ARYL ETHERS; ETHERIFICATION; BOND-CLEAVAGE; hindered; regioselective; KETONES; CROSS-COUPLINGS; intermolecular nucleophilic aromatic substitution; CHEMISTRY; amination; DERIVATIVES

Multifunctional groups diarylamines, an innovative product, efficiently produced from arylamines and p‐nitrosoanisole derivatives by intermolecular SNAr under weak acid conditions. This SNAr proceeds under mild reaction conditions, and more significantly, the substrates involved do not necessarily r...