Effects of Smoking and Smoking Cessation on Endothelial Function: 1-Year Outcomes From a Randomized Clinical Trial

• Published in: Journal of the American College of Cardiology Vol. 55; no. 18; pp. 1988 - 1995
• Main Authors: JOHNSON, Heather M, GOSSETT, Linda K, PIPER, Megan E, AESCHLIMANN, Susan E, KORCARZ, Claudia E, BAKER, Timothy B, FIORE, Michael C, STEIN, James H
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier 04.05.2010; Elsevier Limited
• Subjects: Atherosclerosis; Biological and medical sciences; Blood pressure; Brachial Artery - physiopathology; Carbon monoxide; Cardiology; Cardiology. Vascular system; Cholesterol; Cholesterol, LDL - blood; Cigarettes; Clinical trials; Confidence intervals; Double-Blind Method; Endothelium, Vascular - physiopathology; Female; Humans; Male; Medical sciences; Nicotine; Smoking - blood; Smoking - physiopathology; Smoking Cessation; Studies; Time Factors; Tobacco, tobacco smoking; Toxicology; Ultrasonic imaging; Ultrasonography, Doppler; Vasodilation; Veins & arteries; Weight Gain; Randomization; Prognosis; Tobacco smoking; Clinical trial; Circulatory system; Endothelial function; Cardiology

The purpose of this study was to determine whether smoking cessation improves flow-mediated dilation (FMD) of the brachial artery. The long-term effects of continued smoking and smoking cessation on endothelial function have not been described previously. This was a 1-year, prospective, double-blind...