Tanshinol suppresses endothelial cells apoptosis in mice with atherosclerosis via lncRNA TUG1 up-regulating the expression of miR-26a

• Published in: American journal of translational research Vol. 8; no. 7; pp. 2981 - 2991
• Main Authors: Chen, Chao, Cheng, Guangqing, Yang, Xiaoni, Li, Changsheng, Shi, Ran, Zhao, Ningning
• Format: Journal Article
• Language: English
• Published: United States e-Century Publishing Corporation 01.01.2016
• Subjects: Original; atherosclerosis; cell apoptosis; endothelial cells; miR-26a; lncRNA TUG1; Tanshinol

Endothelial cell (EC) apoptosis is a crucial process for the development of atherosclerosis. Tanshinol is reported to protect vascular endothelia and attenuate the formation of atherosclerosis. However, the potential molecule mechanism of the protective role of tanshinol in atherosclerosis need to b...