Impaired left ventricular filling in COPD and emphysema: is it the heart or the lungs? The Multi-Ethnic Study of Atherosclerosis COPD Study

• Published in: Chest Vol. 144; no. 4; p. 1143
• Main Authors: Smith, Benjamin M, Prince, Martin R, Hoffman, Eric A, Bluemke, David A, Liu, Chia-Ying, Rabinowitz, Dan, Hueper, Katja, Parikh, Megha A, Gomes, Antoinette S, Michos, Erin D, Lima, João A C, Barr, R Graham
• Format: Journal Article
• Language: English
• Published: United States 01.10.2013
• Subjects: Aged; Female; Heart - physiopathology; Humans; Lung - physiopathology; Male; Middle Aged; Prospective Studies; Pulmonary Disease, Chronic Obstructive - complications; Pulmonary Disease, Chronic Obstructive - physiopathology; Pulmonary Emphysema - complications; Pulmonary Emphysema - physiopathology; Ventricular Dysfunction, Left - etiology

COPD and heart failure with preserved ejection fraction overlap clinically, and impaired left ventricular (LV) filling is commonly reported in COPD. The mechanism underlying these observations is uncertain, but may include upstream pulmonary dysfunction causing low LV preload or intrinsic LV dysfunc...