Hypersensitivity Pneumonitis: Radiologic Phenotypes Are Associated With Distinct Survival Time and Pulmonary Function Trajectory

• Published in: Chest Vol. 155; no. 4; pp. 699 - 711
• Main Authors: Salisbury, Margaret L, Gu, Tian, Murray, Susan, Gross, Barry H, Chughtai, Aamer, Sayyouh, Mohamed, Kazerooni, Ella A, Myers, Jeffrey L, Lagstein, Amir, Konopka, Kristine E, Belloli, Elizabeth A, Sheth, Jamie S, White, Eric S, Holtze, Colin, Martinez, Fernando J, Flaherty, Kevin R
• Format: Journal Article
• Language: English
• Published: United States American College of Chest Physicians 01.04.2019
• Subjects: Alveolitis, Extrinsic Allergic - diagnosis; Alveolitis, Extrinsic Allergic - mortality; Biopsy; Diffuse Lung Disease; Female; Follow-Up Studies; Humans; Lung - diagnostic imaging; Male; Middle Aged; Phenotype; Prognosis; Radiography, Thoracic; Respiratory Function Tests - methods; Retrospective Studies; Survival Rate - trends; Tomography, X-Ray Computed; United States - epidemiology; United States; interstitial lung disease; prognostic model; pulmonary fibrosis

Hypersensitivity pneumonitis (HP) is an interstitial lung disease with a better prognosis, on average, than idiopathic pulmonary fibrosis (IPF). We compare survival time and pulmonary function trajectory in patients with HP and IPF by radiologic phenotype. HP (n = 117) was diagnosed if surgical/tran...