Calcium and barium permeable channels from Aplysia nervous system reconstituted in lipid bilayers

• Published in: The Journal of membrane biology Vol. 97; no. 3; p. 205
• Main Authors: Coyne, M D, Dagan, D, Levitan, I B
• Format: Journal Article
• Language: English
• Published: United States 01.01.1987
• Subjects: Animals; Aplysia; Barium - metabolism; Calcium - metabolism; Electric Conductivity; Ganglia - physiology; In Vitro Techniques; Ion Channels - physiology; Lipid Bilayers; Membrane Potentials; Permeability; Phosphatidylethanolamines; Phosphatidylserines

Ion channels permeable to barium and calcium were reconstituted from the Aplysia nervous system into phospholipid bilayers formed on the tips of patch electrodes. With asymmetrical concentrations of barium or calcium on the two sides of the bilayer, the single-channel currents reversed at the calcul...