Methacholine challenge : Comparison of two methods

• Published in: Chest Vol. 127; no. 3; pp. 839 - 844
• Main Authors: COCKCROFT, Donald W, DAVIS, Beth E, TODD, David C, SMYCNIUK, Audrey J
• Format: Journal Article
• Language: English
• Published: Northbrook, IL American College of Chest Physicians 01.03.2005
• Subjects: Adult; Aerosols; Aged; Asthma; Asthma - diagnosis; Asthma - physiopathology; Biological and medical sciences; Bronchial Provocation Tests - methods; Bronchoconstrictor Agents; Cardiology. Vascular system; Confidence intervals; Female; Forced Expiratory Volume; Humans; Male; Medical sciences; Methacholine Chloride; Methods; Middle Aged; Pneumology; Total Lung Capacity; s: airway responsiveness; Induced bronchoconstriction; Respiratory disease; methods; Cardiovascular disease; bronchoprovocation; Method; Technique; methacholine; Comparative study; Provocation test

Guidelines for the 2-min tidal-breathing and the five-breath dosimeter methods for methacholine challenge have recently been published by the American Thoracic Society (ATS). Although subjects are exposed to twice as much aerosol at any given concentration during the tidal-breathing method compared...